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(12, 13) By improving glycemic control, enhancing insulin sensitivity, and reducing adiposity, GLP-1 therapies may decrease bone marrow adipose tissue (BMAT) formation and mitigate the harmful effects of hyperglycemia on bone quality
Patients should discuss any sleep-related issues with their healthcare provider, who may adjust the timing of the medication or recommend strategies to improve sleep
In addition to the highly publicized weight benefits, these drugs, like semaglutide, have given the magnitude of benefit with a 20-25% reduction in cardiovascular disease events regardless of weight loss achieved. The Viewpoint authors reference a survey published in 2023, which found that while 45% of U.S
Aich, J
20 TECOS (2015) did not show an increased risk of HF in patients taking sitagliptin for treatment of type 2 diabetes
