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MP-treated mice exhibited dysbiosis of the gut microbiota, disruption of intestinal barrier integrity, increased permeability of metabolic toxins into the systemic circulation, and vascular remodeling, cardiac hypertrophy, and fibrosis, all of which are associated with hypertension [50]

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This directly indicated increased tolerance to virus infection stress could be an effect of co-involvement of GSH and NPR1 which was observed in tolerant interaction of tobacco with other types of pathogens ( Nicotiana tabacum ) and in constitutive GSH synthesis during potato virus X (PVX) accumulation control in Nicotiana benthamiana ( NTN and TuMV on susceptible and resistant (with hypersensitive response or hypersensitive-like, HR or HR-like) respectively on potato and rbohF and rbohD/f mutants of Arabidopsis ( Figure 2 )

Annals of the New York Academy of Sciences, 1033 , 132138

MT-II treatment, n = 8)