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But side effects, drop-off, and variability all emerge in the continuity phase

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Heres what to know: Hunger may still appear, but fullness comes sooner Emotional or habit-based hunger can linger at first Cravings often ease before hunger fully quiets Appetite suppression strengthens with dose adjustments Many people notice they can eat less, even if hunger cues are still present

Unlike GLP-1 agonists, which primarily act by delaying gastric emptying and enhancing insulin secretion, BRP operates via the following mechanisms: Hypothalamic activation : BRP triggers the expression of the FOS gene, a key marker of neuronal activation associated with appetite suppression, in the hypothalamus