Compared to other secretagogues, it appears to show limited activity toward prolactin or cortisol pathways
Notably, no lethal dose could be determined in animals (no LD50 established)
While blood clots are not a recognized side effect of GLP-1 medications, patients should remain aware of warning signs, particularly given that obesity itself increases thrombotic risk
Since B12 is mainly found in animal products like meat, eggs, and dairy, vegans and older adults are most at risk of deficiency
JACC 82(9):833955 Rangaswami J, Bhalla V, de Boer IH, Staruschenko A, Sharp JA, Singh RR et al (2020) Cardiorenal protection with the newer antidiabetic agents in patients with diabetes and chronic kidney disease: a scientific statement from the American Heart Association