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These pathways could be critical in the metformin-mediated delay of abnormal fat deposition and fibrosis in MAFLD
When growth hormone reaches the liver, it stimulates the release of IGF-1, which in turn does a number of things that are both synergistic and different
Insulin stimulates the clonogenic potential of angiogenic endothelial progenitor cells by IGF-1 receptor-dependent signaling
doi: 10.1089/acm.2006.12.881
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