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For extra hydration, a serum containing hyaluronic acid can be applied before the cream
The structural basis for this stability is not fully elucidated but may relate to its high proline content (3 consecutive Pro residues) which confers rigidity and protease resistance
Prescribing information notes that allergic-type reactions, including anaphylactoid symptoms, have been reported in rare cases
Parlesak A 1 , Bode C, Bode JC
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