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Referencias Food and Drug Administration

A 2023 Lancet publication studied Retatrutide in people with type 2 diabetes in a Phase 2 research setting

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Whether declining MOTS-c is a cause or consequence of this deterioration is still being resolved, but the correlation is striking enough that some researchers have proposed plasma MOTS-c as a biomarker of mitochondrial vitality and metabolic age

Significant weight loss usually begins around 8 to 12 weeks, with patients losing an average of 5% to 10% of their body weight within the first six months of treatment