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The SELECT trial (2023) demonstrated a 20% reduction in major adverse cardiovascular events in non-diabetic obese patients establishing cardiovascular research as a major frontier for GLP-1 agonist compounds
Head-to-Head Comparison The most direct comparison came from the SURMOUNT-5 trial, which evaluated tirzepatide compared to semaglutide in adults with obesity
Rare but serious risks include pancreatitis
The Impact of Rapid Weight Loss on Thyroid Markers Even in individuals without a pre-existing thyroid condition, significant weight loss can lead to changes in thyroid function markers
Moreover, the AHI markedly decreased, accompanied by improvements in daytime sleepiness and sleep architecture normalization
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