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In early trials, beta-carotene was used in AREDS2 supplements, but beta-carotene usage nearly doubled the risk of lung cancer

It helps inhibit the production of melanin, the pigment responsible for dark spots and uneven skin tone, resulting in a more radiant and even appearance

Published cosmetic studies have used concentrations in the low parts-per-million range to produce measurable fibroblast stimulation

Polyphenols are intensively metabolized in the human gastrointestinal tract after apple juice consumption

Oral delivery is pharmacokinetically disadvantaged versus injection for systemic targets, but may have a genuine local advantage for GI-tract applications because degradation products act locally before absorption