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Add-on therapy with dulaglutide 1.5 mg weekly (but not 0.75 mg) to baseline SGLT2 inhibition in AWARD-10 resulted in 0.9 kg additional weight loss compared to placebo, while add-on therapy with semaglutide 1 mg weekly in SUSTAIN-9 resulted in an additional 3.1 kg weight loss versus placebo 51 , 52

Conclusion GLP-1R agonists have revolutionized diabetes and obesity management , but their role in perioperative care remains complex

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