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The Risks In the use of the SGLT-2s, the sugar doesn't need to be necessarily high, says Trence
For example, its only measuring whether youre primarily using carbs or fat as fuel
Higher doses or additional medications Repeated injections without sustained improvement Increasing side effects with diminishing therapeutic return At this stage, pain is no longer simply a symptomit reflects underlying regulatory imbalance
Both groups received the maximum tolerated dose of their medication: Tirzepatide group: 10 mg or 15 mg weekly (Zepbound) Semaglutide group: 1.7 mg or 2.4 mg weekly (Wegovy) Participants had a BMI of 30 or higher, or a BMI of 27 or higher with at least one weight-related health condition
Obesity is a multifaceted disease that contributes directly and indirectly to atherosclerotic CVD, heart failure, atrial fibrillation and multiple CVD risk factors, including dyslipidaemia, type 2 diabetes, hypertension and sleep disorders (Figure)
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