More recent publication years correlated with a smaller effect size ( 0.19
For example, in rheumatoid arthritis (RA), cartilage and bone destruction are mediated by fibroblasts that fail to switch-off, leading to persistent activation of immune cells, resulting in chronic inflammation ( One of the endogenous pro-resolving pathways that has extensively been studied at the preclinical and clinical levels, and indeed has reached approval for use in humans, is the targeting of the melanocortin pathway ( in vitro , in vivo , and clinical investigations
However, the induction of CYP3A4 by turmeric has not been reported in humans
Still, let's have fun with the irony
McKeever TM, Scrivener S, Broadfield E, Jones Z, Britton J, Lewis SA