For those using B12 for general wellness, the effects can be more graduala steady feeling of being more energized and focused over time
It might be a very minor effect
In Hep3B cells, SFN not only decreased cell viability but also inhibited telomerase activity via reducing the expression of telomerase reverse transcriptase in a ROS-dependent manner, suggesting a novel mechanism of the antineoplastic activity of SFN (Moon et al., 2010)

The full ingredient list: Ingredients: Aqua (Solvent), Tetrahexyldecyl Ascorbate (Antioxidant), Dimethicone (Skin conditioning agent), Glycerin (Humectant), C9-12 Alkane (Emollient), Ascorbyl Glucoside (Skin brightening agent, Silica (Opacifying agent), Pyrus Malus (Apple) Fruit Extract (Skin conditioning agent), Hydrogenated Lecithin (Skin conditioning agent), Polyglyceryl-6 polyricinoleate (Emollient), Mannitol (Skin conditioning agent), Sodium Hydroxide (Solvent), Acrylates/C10-30 Alkyl Acrylate Crosspolymer (Viscosity controlling agent), Xanthan Gum (Emulsion stabilizer), Glutathione (Antioxidant), Ergothioneine (Antioxidant), Oryza Sativa (Rice) Bran Extract (Skin conditioning agent), Hydroethyl Acrylate/Sodium Acryloylmethyl Taurate Copolymer (Dispersing agent), Cetyl Alcohol (Emulsion stabilizer), Caprylyl Glycol (Skin conditioning agent), Lysine Carboxymethyl Cysteinate (Skin conditioning agent), Coco-Caprylate/Caprate (Skin conditioning agent), Tocopherol (Skin conditioning agent), Sodium Citrate (pH adjuster), Sodium Phytate (Chelating agent), Hexylene Glycol (Emulsifier), Ethylhexylglycerin (Skin conditioning agent), Helianthus Annuus (Sunflower) Extract (Emollient), Urea (Humectant), Caprylic/Capric Triglyceride (Skin conditioning agent), Sodium PCA (Skin conditioning agent), Rosmarinus Officinalis (Rosemary) Leaf Extract (Skin conditioning agent), Polysorbate 60 (Surfactant), Sorbitan Isostearate (Surfactant), Trehalose (Humectant), Ascorbic Acid (Skin conditioning agent), Glucose (Solvent), Vanilla Planifolia Fruit Extract (Skin conditioning agent), Polyquaternium-51 (Humectant), Triacetin (Solvent), Sodium Hyaluronate (Skin conditioning agent), Phenoxyethanol (Preservative)

If we see that pounds are going down but their body fat percentage is staying the same and their muscle mass is decreasing, we can modify lifestyle components such as their type and frequency of exercise and food intake, for instance." "Regular communication and motivation are crucial to helping patients stay on track