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GAPDH and Histone-H3 served as loading controls

This type of study is important for several reasons: it tells us how long the peptide remains active in the body, what breakdown products are formed (which could themselves have biological activity or be used as markers in drug testing), and helps explain why AOD9604 needs to be administered in certain ways to remain effective

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Unknown long-term profile: While short- and mid-term studies show good tolerability, the long-term safety of chronic Cagrilintide use is still being evaluated in Phase III trials