micro tirzepatide Microdose What Is Microdosing Tirzepatide?

Viollet, B., Kahn, A

trial evidence (STEP 1, SURMOUNT-1) shows large average weight loss alongside cardiovascular and metabolic benefit

There is a noted theoretical risk of thyroid tumors based on animal studies

This change can be life-altering, allowing patients to focus on their lifestyles and well-being

GLP-1Rs are expressed in the pancreas, intestinal intraepithelial lymphocytes, myocardium, adipose tissue, kidney, liver, blood vessels, lungs and in the CNS.2,3 Although GLP-1 is known for its incretin effect, which it shares with glucose-dependent insulinotropic peptide (GIP), the intake-regulating action, essential for its efficacy against obesity, occurs through its interaction with receptors located in the CNS.1,5 The GLP-1 peptide can reach the central nervous system (CNS) via peripheral vagal afferents, which transmit its action through the nodose ganglion to the nucleus tactus solitarius (NTS)