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GLP-1 is involved in the regulation of energy balance (Holst, 2007), and its activation and subsequent binding to the GLP-1R reduces food intake and, consequently, body weight (Turton et al., 1996)

Generally, Aetna requires a BMI of 30 or greater, or a BMI of 27 or greater with at least one weight-related health condition like high blood pressure, high cholesterol, or sleep apnea

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