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The MTHFR gene has been identified to possess 14 common or rare single nucleotide polymorphism that are associated with enzymatic deficiency 14

However, most patients do not exhibit specific symptoms in the early stages of OC and CA125 has limited sensitivity and specificity for early cancer detection (Liu et al., 2020)

Researchers measure lesion area via endoscopic or gross pathology examination, alongside molecular markers of inflammation such as TNF-alpha, IL-1 beta, and COX-2 expression in gastric tissue samples

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15, 18, 48 The colon in claudin-2 TG mice is significantly longer than that of their littermates and their colonic epithelial proliferation is also upregulated