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First, its important to monitor for signs of hypoglycemia (low blood sugar), especially if [either drug is] used with other diabetes medications, says Shapiro

All three require subcutaneous injection once weekly

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Commonly reported side effects include: Nausea and vomiting Diarrhoea or constipation Decreased appetite (which may be pronounced) Abdominal discomfort or bloating Injection site reactions (redness, bruising, or mild pain) Increased heart rate (a recognised class effect) In clinical trials, the majority of gastrointestinal side effects were described as mild to moderate in severity and tended to resolve over time as the body adjusted to the medication