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10.1515/revneuro-2015-0021 50 KanetoH.ObataA.KimuraT.ShimodaM.KinoshitaT.MatsuokaT

Black box warnings do get revised or removed as more evidence is presented

Accordingly, within the proposed diagnostic model, Tier 1 structural assessment relies on established clinical imaging modalities such as MRCP and endoscopic ultrasound, whereas quantitative radiomics and AI-driven texture analysis are positioned within Tier 3 as investigational tools intended for future integration

This activation reduced neuroinflammation and restored levels of key synaptic proteins [69]

Curr Neuropharmacol 9:195199 Suchy J, Chan A, Shea TB (2009) Dietary supplementation with a combination of alpha-lipoic acid, acetyl-l-carnitine, glycerophosphocoline, docosahexaenoic acid, and phosphatidylserine reduces oxidative damage to murine brain and improves cognitive performance