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[14] Together, these data support the continued use of metformin across the GLP-1 RA care journey without additional safety compromise
Plus, it enhances blood vessel growth and circulation, making it a top pick for quick recovery after injuries or surgeries
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Additionally, oxidative stress and ROS can originate from xenobiotic bioactivation by prostaglandin H synthase (PHS) and lipoxygenases (LPOs) or microsomal P450s which can oxidize xenobiotics to free radical intermediates that react directly or indirectly with oxygen to produce ROS and oxidative stress [26] as in Fig (2)
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