In one single-center trial of 72 subjects using a controlled-adverse-environment model, the T4 eye drop did not meet its co-primary endpoints (ocular discomfort and inferior corneal staining) at the primary time point, but it did produce statistically significant improvements on several secondary endpoints, including central and superior corneal staining, with no adverse events reported
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Journal References : Michael J
As there was only one study each of exenatide or lixisenatide in the normal BMI group 21,38 , we additionally analyzed the studies with liraglutide (n = 4 for normal BMI studies 20,22,23,39 and n = 8 for overweight/obese BMI studies 28,29,30,32,33,34,37,39 )