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This hypothesis is supported by several studies that have shown supplementation with SAM improves depressive symptoms (104-107)
Long-term use of antiseizure medications is generally discouraged, as medications such as carbamazepine and phenytoin can reduce vitamin B12 and folic acid levels
Sterile Water for Injection (SWFI) is a single-use product with no preservative suitable where only a single-use preparation is needed and multi-access storage is not required
Because AOD9604 is not FDAapproved and cannot be compounded under current guidance, it is offered only under a strict informed consent framework with full transparency about its investigational status, potential risks, and mixed efficacy data
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