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Research in Drosophila melanogaster demonstrated geroprotective effects at concentrations 16,000-80,000,000 times lower than those required for melatonin, suggesting Epithalon functions through highly efficient regulatory mechanisms rather than stoichiometric antioxidant consumption

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While not a primary reason most people pursue this protocol, improved sexual function represents a meaningful quality of life benefit

Co-administration increases total T4 exposure by approximately 33%

Switching locations and allowing each location sufficient time to heal can help keep skin healthy