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While the 1999 study focused on natural adaptations, two decades of research since have explored whether we can support glutathione directly

Ferritin, an important protein for storing iron (Theil, 2004), can avoid cell damage caused by Fenton reaction via combining with excess ferrous iron ( Meanwhile, a paper proposed that ATG5, an autophagy-related gene, regulated ferritinophagy and then induced ferroptosis ( Lipid metabolism Acyl-CoA synthetase long-chain family member 4 (ACSL4) has been confirmed as a key ferroptosis gene, playing a crucial role in the synthesis of long-chain PUFA-CoA (Zhang H