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Patients with a BMI of 40 kg/m or greater, or 35 kg/m or greater with significant comorbidities, may be referred to specialist tier 3 or tier 4 weight management services, depending on local pathways

Headaches Prevalence: Common Symptoms: Headaches, ranging from mild to severe, may occur, especially when beginning treatment or increasing the dose

Differential gene expression between clusters was performed using the FindMarkers function

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