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bright lights, loud noises, strong scents, and cold) Dimension 3 - Common medical comorbidities: Somatic pain disorders Psychiatric conditions Sleep disorders Somatic diseases Dimension 4 - Neurobiological, psychological, and functions consequences: Poor quality of life High costs that indirectly stem from the burden of fibromyalgia Dimension 5 - Putative neurobiological and psychosocial mechanisms, risk factors, and protective factors: Familitary for functional pain disorders Environmental stressors that may trigger fibromyalgia: Early lifetime adverse events Trauma Medical conditions Psychosocial stressors Central sensitization - A Deeper Level Central sensitization can be defined as a state in which the central nervous system amplifies sensory input and creates an enhanced response to sensation (AKA wind-up)

Risks of Improper IGF-1 LR3 Dosing Because IGF-1 stimulates growth pathways, excessive or unsupervised dosing may increase risks, including: Hypoglycemia (low blood sugar) Edema Joint discomfort Nerve compression symptoms Potential overstimulation of mitogenic pathways IGF-1 signaling is also involved in cellular proliferation

NRS-Pain scores decreased in 52% of patients, NRS-Suppuration scores decreased in 53% patients, and improved quality of life, based on DLQI scores, was observed in 50% patients at 6 months

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Once comfortable with the injections, you will be permitted to take the medication home and administer doses yourself