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San Diego: Academic Press

However, under conditions of iron overload, excess Fe 2+ in the LIP undergoes Fenton chemistry with H 2 O 2 , producing excessive ROS, promoting lipid peroxidation, and ultimately triggering ferroptosis (Zhao et al., 2025a)

There are many unknowns, including dose-response in humans, interactions with other fertility treatments, and differences at various stages of conception including gametogenesis, implantation, and gestation

This combination makes it relevant not just for aesthetic outcomes but for the broader inflammatory burden that accelerates aging in metabolically active tissues