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While the evidence regarding GLP-1 receptor expression in testosterone-producing tissues is limited and mixed in humans, the metabolic changes induced by semaglutideparticularly significant weight loss and improved insulin sensitivitycan indirectly affect hormone balance

Physicians should be aware of serious adverse effects to monitor patients accordingly

Physical preparation includes getting baseline measurements and photos if you want to track progress visually, ensuring you understand proper injection technique, and organizing a consistent weekly schedule for injections

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