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Tirzepatide was associated with a lower mortality rate at 12 months

Using a genetically engineered mouse model, the researchers demonstrated that newer small-molecule GLP-1 drugssuch as recently approved oral medicationscan reach deep brain regions

Avoid repeated cycling between warm and cold temperatures, as thermal stress accelerates degradation

Earlier context Frequent cannabis users wake with higher cortisol levels, study finds The earlier article summarized the same study as evidence that frequent cannabis use may dysregulate the HPA axis and potentially worsen long-term stress resilience

The MHRA monitors these medications closely and provides regular safety updates