The dermis, the middle layer of skin where collagen and elastin reside, begins thinning as early as our late twenties
These numbers come from trials where patients were monitored by doctors
LPS induction of a second group of genes (Prdx1, Srxn1, Hmox1, GSH synthase, cysteine transporters), mapping to nrf2 and the oxidative stress response, was increased by GSH depletion
For people who struggled with nausea on tirzepatide, retatrutide offers a slower alternative protocol (2 mg increments over 20 weeks, detailed in our retatrutide dosage guide)
Multiple meta-analyses have shown that creatine supplementation during resistance training augments lean tissue mass by 0.9-1.3 kg compared to placebo and this effect is seen even more prominently in older adults and in people engaged in calorie-restricted protocols