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The predicted translated sequence of the PbGST protein was identical to the one available at PlasmoDB (PBANKA_102390) and was used to generate the 3D structural homology model
The drug tested was called Lixisenatide, which is a glucagon-like peptide-1 receptor agonist, designed primarily for use in diabetes
The choice of 120 mg/dL as a threshold was based on available evidence for a decline of cell function starting above 120 mg/dL in youths with obesity (10, 20)
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