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The metabolic effects of tirzepatide interact with the hormonal environment created by estrogen, progesterone, and testosterone replacement
J Mol Biol
In addition, ameliorating psychotropic drug-related weight gain and potential off-label benefits in other conditions commonly encountered in persons with mental disorders (eg, substance use disorder, alcohol use disorder, binge eating disorder) are also potential near-term clinical applications ( Reports appeared in 2023 of suicidality causally related to the prescription of GLP-1 RAs
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