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Using a lower 7.0% (53 mmol/mol) HbA1c threshold for treatment switching lowered the clinical benefits associated with oral semaglutide but also reduced incremental costs, yielding an ICER of GBP 1514 per QALY gained
Mechanistically, there is no chemical difference
It's an issue they say is likely to get worse especially when it comes to this class of highly sought-after pharmaceuticals
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