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These medications originated to treat type 2 diabetes , and were later approved in the US for weight loss by the Food and Drug Administration (FDA) under Ozempic and Wegovy brand names

In this context, GLP-1R agonists show remarkable potential as an emerging therapeutic agent.GLP-1R agonists reduce body weight, lower blood pressure, and improve lipid levels, as well as exerting anti-inflammatory and antioxidant effects by directly acting on GLP-1R in the heart and blood vessels, thereby reducing the risk of atherosclerotic thrombotic events (Solini et al., 2023)

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Calvani M, Benatti P, Mancinelli A, D'Iddio S, Giordano V, Koverech A, Amato A, Brass EP: Carnitine replacement in end-stage renal disease and hemodialysis

This is a ratio of myoinositol: di-chiro-inositol of 100:1, compared with 0.2:1 in women with PCOS