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An iterative permutation-importance ablation procedure ranked predictors by importance and sequentially removed the least informative variables until a parsimonious subset was obtained

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Morton also emphasizes that weight regain is not a personal failure

The 2020 Aging Pathobiology and Therapeutics review (PMID 35083444) framed the broader anti-ageing framing under which oxidative-stress findings are typically grouped

Topiramate does not affect cardiovascular parameters but requires attention to hydration and kidney stone prevention