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Summary: Retatrutide is currently undergoing extensive Phase 3 clinical trials (the TRIUMPH program), evaluating its efficacy and safety in diverse populations, including those with obesity, type 2 diabetes, established cardiovascular disease, and knee osteoarthritis

Weight reduction decreases vertical force transmission, leading to diminished stimulation of osteoblasts and subsequent net bone resorption

Many commercial plans may cover GLP-1 medications for obesity or metabolic conditions

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