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[1] If during injection a patient experiences chest pain, difficulty breathing, hives, or swelling of the face or throat, it could indicate anaphylactic shock

This increase occurs partly because stomach acid production decreases with age, reducing B12 absorption from food

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bound to TC Excessive vitamin B 12 in the circulation, e.g., such as after injections, usually exceeds the binding capacity of TC and is excreted in the urine