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Category 2 classification restricts licensed compounding pharmacies in the United States from preparing Epitalon for human administration
An exclusive license for commercial development of these amino acid substitutions enabled argenx to build on the pioneering work by Ward and create a novel Ab-based molecule by removing the Fab arms of the full-length IgG1 used in the proof-of-concept studies [115, 119,120,121]
On the other hand, the non-tumorigenic, spontaneously immortalized keratinocyte cell line - HaCaT cells can provide almost unlimited supply of identical cells, ensuring high intra- and inter-laboratory reproducibility
Were all about results
Aug 15 2014;9(16):1557-1566
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