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Research in animal models and population studies suggests GLP-1 receptor agonists may reduce dementia risk and improve cognitive function, but clinical trials are still ongoing
Although the incidence of acute renal failure with the use of GLP-1RA is low there have been several reported cases in the literature (97100)
GLP-1 is involved in the regulation of energy balance (Holst, 2007), and its activation and subsequent binding to the GLP-1R reduces food intake and, consequently, body weight (Turton et al., 1996)
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