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Their use in these populations has been associated with hemoglobin A1c reduction, significant weight loss, and a decrease in long-term microvascular and macrovascular complications ( This mini-review discusses clinical studies evaluating adjuvant treatment with GLP-1RA in patients with T1D as an opportunity to improve glycemic control, achieve weight loss, and decrease total daily insulin (TDI) requirements in these patients

Kores et al., 2022

Although these initial studies directly manipulate GLP-1R or GLP-1, other ways to influence the GLP-1 pathway are less studied

Therefore, adequate availability of carnosine in skeletal muscle will be beneficial for healthy ageing