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My general framework: Start with semaglutide if cost is a significant concern, or if there is no strong reason to expect poor tolerance Start with tirzepatide if the patient has tried semaglutide before and struggled with side effects, if faster initial response matters clinically, or if the patients goals require larger total weight loss Switch to tirzepatide if a patient on semaglutide is experiencing persistent nausea or has plateaued and escalation options are limited One pattern worth noting: men I see a consistent pattern with male patients who struggle to tolerate semaglutide nausea and GI disruption can be particularly disruptive for them, and theyre often less willing to push through it
A review of existing literature using keywords such as oral semaglutide, obesity and weight loss revealed a lack of reliable data on the use and efficacy of oral semaglutide, at doses approved for type 2 diabetes, in individuals with obesity but without diabetes
Mild Headaches or Brain Fog: Cerebral tissue is highly sensitive to fluid shifts
We recommend that all patients having a possible life-threatening emergency call 911
If youre ready to begin your weight loss journey with Compounded Semaglutide, contact Elite Health Center NYC today to schedule your consultation
