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Rare but serious effects can include pancreatitis, gallbladder problems, kidney injury (often linked to dehydration from severe vomiting or diarrhea), severe or persistent abdominal pain, serious allergic reactions, worsening of diabetic retinopathy in people with type 2 diabetes, and low blood sugar especially if semaglutide is combined with insulin or sulfonylureas

Studies show that up to 50 mg is most effective

On the other hand, when patients discontinue GLP-1s, their weight regain is typically incremental to how quickly and how much they lost while taking the medicine, Buie said

Its important to be clear: No clinical trials in menopausal women exist

It's important to follow a healthcare provider's recommendation to tailor the frequency to your specic health prole