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The model was first fitted to the training concentrations (37.5 and 25 M doxorubicin), and then used to simulate the test concentrations (50, 12.5 and 10 M doxorubicin) as a means of blind validation, showing good accordance between the experimental and in silico outputs for all concentrations of doxorubicin
This combo provides the internal defense system necessary to counteract those external factors
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This unusual bell-shaped dose response curve suggests the peptide operates through mechanisms that remain effective even at very low concentrations
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