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Although current clinical treatments, including nonsteroidal anti-inflammatory drugs, glucocorticoids, and immunosuppressants, can alleviate symptoms, their long-term use is often associated with adverse effects such as gastrointestinal damage, hepatorenal dysfunction, and increased risk of infections, which significantly limit their clinical application (35)
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Effect of Ala-Glu-Asp-Gly peptide on life span and development of spontaneous tumors in female rats exposed to different illumination regimes
Teplova et al., 2013
This further resulted in disrupting mitochondrial functioning and enhanced ROS accumulation, enhancing lung cancer ferroptosis therapy [427]
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