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Optimising hydration is fundamental, particularly during treatment initiation when gastrointestinal side effects peak
The cells were resuspended in the desired growth media to an initial optical density (OD 600 ) of 0.1
PLoS ONE 6(4):e18815 Jose N, Joel A, Selvakumar RJ, Ramireddy J, John AO, Georgy JT, Singh A, Ram TS (2022) Diagnosis and management of 5-fluorouracil (5-FU)-induced acute leukoencephalopathy: lessons learnt from a single-Centre case series
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RT-PCR analysis revealed significant downregulation of key inflammatory genes, including interleukin-1 beta (IL-1), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-), nuclear factor kappa B (NF-B), and inducible nitric oxide synthase (iNOS), along with a significant reduction in systemic inflammation, as indicated by decreased high-sensitivity C-reactive protein (hsCRP) levels, as well as apoptosis caspases activities
