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Compared with those in normal skin fibroblast subpopulations, the expression levels of senescence- and inflammation-associated genes, including p16 (also known as CDKN2A ), SFRP4 18 , IGF1 19 , and IL1R1 were increased in keloid mesenchymal fibroblasts, whereas CCND2 , IL-6 , CXCL3 , and IL1R1 were increased in keloid pro-inflammatory fibroblasts (Fig
The membrane was blocked with 3% non-fat milk (BioRad, Hercules, CA, United States) at room temperature for 1.5 h, washed, and incubated with primary antibodies (Supplementary Table 3) at 4C overnight on a rotating shaker

However, these potential benefits are largely inferred from its general role in cellular health rather than from direct clinical evidence linking it to increased hair growth

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