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The dose of L-carnitine used in the present study (80 mg/kg) has been employed previously in humans, without adverse effects, for the treatment of different primary or secondary disturbances of the levels of this important metabolic component 26, 27

Approximately 20-30 hours, compared to roughly 12-15 hours for native IGF-1

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This reduced rate of death in culture resulted in extended survival (up to 40 days) of rat sensory neurons in primary culture [15]