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Perhaps the best single paper on this topic comes from Oprea and colleagues and was published in the British Journal of Anaesthesia in July 2025

In addition to helping with insulin resistance, these medications can benefit those with PCOS in other ways: by promoting weight loss, regulating menstrual cycles, reducing chronic inflammation, and lowering the risk of cardiovascular disease and non-alcoholic fatty liver disease, conditions that can be associated with PCOS

It is not proteinogenic (protein creating), but is important to cellular processes, including selenium homeostasis and thyroid hormone metabolism