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People's back pain can change, getting worse with hard work, stress, or what they eat

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57 When combined with the non-steroidal anti-inflammatory drug (NSAID) meloxicam (Vivlodex), a micronized curcumin/palmitoyl-glucosamine complex that provided 266798 mg palmitoyl-glucosamine plus 133399 mg curcumin per day, depending on body weight, allowed for the reduction of meloxicam dose (by up to 25%) while maintaining the same degree of pain mitigation based on veterinarian evaluations

Chondroitin sulfate is the main component of glial scars, and the enzyme chondroitin sulfate ABC reduces it.[ref] Another animal study used melatonin for six weeks on sciatic nerve injuries