Multiple sclerosis, a condition that can affect the brain and spinal cord, can also be managed with this formulation
Tanguy S, Morel S, Berthonneche C, Toufektsian M-C, de Lorgeril M, Ducros V, et al
Although these species are generated during normal cellular metabolism and participate in essential physiological processes like signal transduction and gene expression at low concentrations (Krishnamurthy et al., 2024), their excessive accumulation or insufficient scavenging leads to oxidative stress, causing damage to vital biomolecules and cellular structures
the authors call for larger trials
One hypothesis from researchers at Harvard Medical School: chronic NNMT suppression might alter methylation donor availability, since NNMT consumes S-adenosylmethionine (SAM) as a methyl donor